Thursday, December 6, 2012

Tips To Becoming An Excellent Bed And Breakfast Host | Oregon ...

It is surely a common thing for a place offering a lot of amusements to gain lots of visitors. Indeed, i t will be unnatural if the beautiful place is not being enjoyed by other people. Since there are many visitors who will come to a certain place to enjoy the scenery or the amusements, it is only natural to find a lot of Ann Arbor bed and breakfast inns.

To become a good host, there are various things that the owner should consider. Here are some of the tips that might be of great importance to him. Of course, these tips will surely help the owner create a good impression to leave the guest with.

For the first tip, it is only appropriate for the owner to leave flyers or leaflets of where they can order pizza in the room of the guest. A lot of people who are traveling nowadays find it more appealing to eat pizza while staying at their room. It is also a responsibility of the owner to tell the guest whether it is fine to eat at the patio, at the deck, or at the room.

Show that the staff is accommodating by telling the guest that they should ask in case they need something. He should tell the guest whom to ask if he really has something he needs. If the guest wants to have extra towels, pillows, blankets, or iron and ironing board, he should be ready to accommodate to them.

It is also up to the host to consider whether it is all right to put up a collection of the recipes that they might be able to share with the guests. These recipes are oftentimes considered to be one of the highlights of staying within the said housing facility. The host will be the one to decide if it will come with a fee or not.

Most of the hosts will also cater to their guests who have interest in their hobby. There are hosts that like to indulge themselves in pottery making or quilt making. If the guests are interested in these activities as well, the host can ask them to go and watch him as he is progressing with his work.

Those inns that have a historic value may want to put together a scrap book. With the scrap book, it should be easy for the guest to know more about the history of the inn that he has chosen to stay in. The scrap book may be displayed in a public area or be placed one copy per room.

There is also the need for the host to provide the guests with the list of the churches within the area. If possible, he should also include the times for the worship service. Of course, he has to make sure that the list is updated as to avoid embarrassing the guest.

Do not forget to be sensitive to the privacy and space that his guests need. They should be given these things so that they can feel at ease. A good Ann Arbor bed and breakfast is one which will allow the guest to feel as if they are staying at their second home while in the said inn.

When a weekend getaway is desired, locals may check out Ann Arbor Bed and Breakfast at www.a2vitosha.com to book a reservation. You will learn about their rates, amenities, and attractions when you click the links at http://www.a2vitosha.com today.

Source: http://oregonattractions.net/travel-leisure/tips-to-becoming-an-excellent-bed-and-breakfast-host/

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Wednesday, December 5, 2012

Nokia Lumia 620 announced: 3.8-inch WVGA display, 5MP camera, $249

Nokia announces Lumia 620 Windows Phone 8 handset 38inch WVGA display, 5MP camera, $249

Nokia has announced a surprise new Windows Phone 8 member at LeWeb 2012 in Paris today -- the Lumia 620. The entry-level handset has a 3.8-inch TFT screen running at WVGA resolution (800 x 480), a 1GHz dual-core Snapdragon S4 Plus processor, half a gig of RAM and 8GB of internal storage, expandable by microSD (up to 64GB cards supported). A 5-megapixel shooter with LED flash capable of recording 720p video occupies the back, while a VGA camera is up front for those self-portraits. Connectivity-wise, you'll get online via WiFi or WCDMA 3G, with NFC and Bluetooth 3.0 taking care of all your sharing and pairing. "Dual-shot color" interchangeable shells mean you'll be able to personalize your handset beyond switching up the Live Tile layout. Excluding taxes and subsidies, the new Lumia will cost $249 dollars when it begins shipping in January next year, first in Asia, then expanding to Europe, the Middle East and other territories later. If you're looking for a Windows Phone 8 handset but don't need the best specs out there, perhaps this is your guy -- the wallet-friendly Lumia 610 generally impressed us, so we've got a feeling this might, too.

Continue reading Nokia Lumia 620 announced: 3.8-inch WVGA display, 5MP camera, $249

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Tuesday, December 4, 2012

Auburn hires ex-assistant Malzahn as head coach

AUBURN, Ala. (AP) ? Auburn has turned to Gus Malzahn to restore a program that made an unprecedented fall two years after winning a national title with Cam Newton operating his high-powered offense to perfection.

The school announced that it will introduce the former Arkansas State coach in a news conference Tuesday night.

Malzahn was the Tigers' offensive coordinator during their 2010 national championship run before heading to Arkansas State for his first college head coaching position.

He led the Red Wolves to a 9-3 record, a Sun Belt Conference title and a berth in the GoDaddy.com Bowl then parlayed that into a job in the powerhouse Southeastern Conference.

"It's an outstanding institution with a storied football program that I had the pleasure of experiencing firsthand for three years," Malzahn said in a statement. He thanked school representatives for their confidence "in my ability to turn this program around and to bring Auburn back to national prominence. This is a homecoming for me and I look forward to being reunited with the Auburn family."

Malzahn, 47, returns with his fast-paced, no-huddle offensive style. He replaces former boss Gene Chizik, who was fired one day after a 49-0 loss to No. 2 Alabama to complete a 3-9 season.

Before his arrival at Auburn in 2009, Malzahn had spent two seasons as Tulsa's offensive coordinator. He was the offensive coordinator at Arkansas for one year after a successful run in the Arkansas high school ranks.

Auburn had the nation's 115th-ranked offense last season, averaging 305 yards a game. The Red Wolves were ranked 19th in total yards under Malzahn.

It's the second straight time Auburn has turned to one of its coordinators from an unbeaten team. Chizik ran the defense for the 13-0 team in 2004 but was hired by the Tigers despite a 5-19 record in two seasons at Iowa State.

"We are tremendously excited that Gus Malzahn will be our next head football coach," athletic director Jay Jacobs said. "Coach Malzahn was the clear unanimous choice of our search committee, and I am pleased that Dr. Gogue has accepted our recommendation. This is a great day for Auburn football and Auburn University."

The search committee was comprised of Jacobs, Auburn Heisman Trophy winners Pat Sullivan and Bo Jackson and former Tigers player Mac Crawford.

Auburn owes more than $11 million in buyouts to Chizik and his coaching staff. Malzahn's contract and salary information was not immediately available.

The Tigers are hoping he can return them to success after a winless SEC season.

"Gus Malzahn is a proven winner," Jacobs said. "He is without question one of the brightest minds in college football and he has won everywhere he has been. Coach Malzahn knows what it takes to build a championship program in the Southeastern Conference. He knows our state and region and he understands what it will take to turn our program around. Coach Malzahn will also be an outstanding ambassador for Auburn University, and that was important to the committee."

The NCAA has been investigating the recruitment of signee Jovon Robinson, who was ruled ineligible after a guidance counselor admitted to creating a fake transcript.

The Tigers badly struggled in a transition to Scot Loeffler's pro-style last season, starting three quarterbacks.

Auburn was ranked in the top seven in rushing, total and scoring offense in 2010 and Newton won the Heisman Trophy in his lone season out of the junior college ranks. It was the Tigers' first national title since 1957.

Without Newton, the Tigers slipped to 100th in total offense in 2011 and then dipped even further.

The hiring reunites Malzahn with the quarterback he recruited out of Arkansas. Kiehl Frazier was benched last season after struggling as the starter. He was USA Today's national offensive player of the year as a high school senior.

Malzahn had been earning $1.3 million a year for the Tigers after interviewing with Vanderbilt after the national championship season. He took a substantial pay cut to join the head coaching ranks with the Sun Belt Conference team. Malzahn replaced Hugh Freeze, who also left after one season at Arkansas State to take over at Mississippi.

Chizik's tenure was marred by off-the-field problems, including the arrest of four players from the championship team for armed robbery.

Malzahn also made a couple of decisions with players that didn't pan out. Tailback Mike Dyer transferred from Auburn ? where he was suspended ? to Arkansas State. He was then dismissed by Arkansas State in July after a state trooper found marijuana and a gun in a car the national title game MVP was driving.

Source: http://news.yahoo.com/auburn-hires-ex-assistant-malzahn-head-coach-223114994--spt.html

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Researchers discover master regulator of skin development

Monday, December 3, 2012

The surface of your skin, called the epidermis, is a complex mixture of many different cell types ? each with a very specific job. The production, or differentiation, of such a sophisticated tissue requires an immense amount of coordination at the cellular level, and glitches in the process can have disastrous consequences. Now, researchers at the Stanford University School of Medicine have identified a master regulator of this differentiation process.

"Disorders of epidermal differentiation, from skin cancer to eczema, will affect roughly one-half of Americans at some point in their lifetimes," said Paul Khavari, MD, PhD. "Understanding how this differentiation occurs has enormous implications, not just for the treatment of disease, but also for studies of tissue regeneration and even stem cell science." Khavari is the Carl J. Herzog Professor and chair of the Department of Dermatology.

Khavari and his colleagues have found that, like a traffic cop motioning cars to specific parking spaces in a large, busy lot, a newly identified molecule called TINCR is required to direct precursor cells down pathways toward particular developmental fates. It does so by binding to and stabilizing differentiation-specific genetic messages called messenger RNAs. Blocking TINCR activity, the researchers found, stopped the differentiation of all epidermal cells.

"This is an entirely unique mechanism, which sheds light on a previously invisible portion of the regulation of this process," said Khavari, who is also a member of the Stanford Cancer Institute and chief of the dermatology service at the Veterans Affairs Palo Alto Health Care System. He is the senior author of the research, which will be published online Dec. 2 in Nature. Former Stanford postdoctoral scholar Markus Kretz, PhD, is the first author. Kretz is now an assistant professor of biology at the University of Regensburg in Germany.

Surprisingly, this coordinator extraordinaire is not a protein. (Proteins have traditionally been thought to be the primary movers and shakers in a cell, although that view is now changing somewhat.) Instead, it belongs to a relatively new, and increasingly influential, class of regulatory molecules called long, non-coding RNAs, or lncRNAs. These molecules are so named because they do not carry instructions to make proteins. They are also longer than other regulatory RNAs known as microRNAs.

But even among lncRNAs, TINCR, and its role in epidermal differentiation, is unique.

"This work revealed a new role for regulatory RNAs in gene activation ? by stabilizing select messenger RNA transcripts," said co-author Howard Chang, MD, PhD, professor of dermatology. "This finding highlights the ability of regulatory RNAs to fine-tune gene expression."

The researchers identified the molecule by looking for RNAs that are more highly expressed in differentiating epidermal cells called keratinocytes than in progenitor cells. They found that levels of TINCR (short for "terminal differentiation-induced non-coding RNA") expression were 150 times greater in the keratinocytes. But to figure out what TINCR was doing, they had to develop two new assays: one to help researchers identify interactions between RNA molecules, and another to suss out interactions between a regulatory RNA and its protein partners. Such techniques will become increasingly important as researchers continue to identify the critical regulatory roles played by RNA molecules.

"These long, non-coding RNAs don't have recognizable, classic motifs like proteins do," said Khavari. "And yet, we really need to know with what other molecules they may be physically interacting to truly understand their biological roles."

The first approach, which the researchers termed RIA-Seq, couples an RNA interaction assay with a deep-sequencing technique to identify RNA partners of TINCR. Using RIA-Seq, the researchers found that TINCR and its RNA partners ? many of which encode instructions for proteins essential to the differentiation process ? share a common, short sequence that mediates their binding.

"These conserved, complementary motifs may help TINCR pair up with and stabilize its partner messenger RNAs," said Khavari. "In this way, TINCR may serve as a scaffold for many mRNAs involved in epidermal differentiation."

The second approach used a grid, or microarray, of 9,400 human proteins to which the researchers exposed TINCR. One of the proteins, termed STAU1, bound strongly to TINCR. STAU1 had not previously been implicated in epidermal differentiation, but the researchers found that blocking its activity prevented differentiation in a manner similar to blocking TINCR.

"This effect is quite specific for epidermal tissue," said Khavari, "and it suggests that nature has evolved a simple mechanism to control the tissue-specific expression of a large number of genes. We'd like to understand more about this TINCR-STAU1 complex to get a better idea of how it acts at a biochemical level."

In addition to identifying a unique role for a new lncRNA in epidermal differentiation, Khavari and Chang said they are excited to have developed new tools to understand how these regulatory RNAs function in the cells. "This really helps substantially expand our tool kit that we can use to analyze how RNAs and proteins interact," said Khavari.

###

Stanford University Medical Center: http://med-www.stanford.edu/MedCenter/MedSchool

Thanks to Stanford University Medical Center for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/125652/Researchers_discover_master_regulator_of_skin_development

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Fighting surges around Syrian capital of Damascus

In this photo released by the Syrian official news agency SANA, an injured Syrian student, lies at a hospital bed after he was wounded when a mortar hit the al-Batiha school in al-Wafideen camp, about 25 kilometers (15 miles) northeast of Damascus, Syria, Tuesday Dec. 4, 2012. A mortar slammed into a ninth-grade classroom in the Damascus suburbs on Tuesday, killing 29 students and a teacher, according to state media, as the civil war closed in on President Bashar Assad's seat of power. (AP Photo/SANA)

In this photo released by the Syrian official news agency SANA, an injured Syrian student, lies at a hospital bed after he was wounded when a mortar hit the al-Batiha school in al-Wafideen camp, about 25 kilometers (15 miles) northeast of Damascus, Syria, Tuesday Dec. 4, 2012. A mortar slammed into a ninth-grade classroom in the Damascus suburbs on Tuesday, killing 29 students and a teacher, according to state media, as the civil war closed in on President Bashar Assad's seat of power. (AP Photo/SANA)

NATO Secretary General Anders Fogh Rasmussen speaks at a media conference during a meeting of NATO foreign ministers at NATO headquarters in Brussels on Tuesday, Dec. 4, 2012. NATO foreign ministers are expected to approve Turkey's request for Patriot anti-missile systems to bolster its defense against possible strikes from neighboring Syria. (AP Photo/Yves Logghe)

Greek Foreign Minister Dimitris Avramopoulos, center right, speaks with German Foreign Minister Guido Westerwelle, center left, during a group photo at a meeting of NATO foreign ministers at NATO headquarters in Brussels on Tuesday, Dec. 4, 2012. NATO foreign ministers are expected to approve Turkey's request for Patriot anti-missile systems to bolster its defense against possible strikes from neighboring Syria. (AP Photo/Virginia Mayo)

Greek Foreign Minister Dimitris Avramopoulos, left, speaks with British Foreign Minister William Hague, front center, during a group photo at a meeting of NATO foreign ministers at NATO headquarters in Brussels on Tuesday, Dec. 4, 2012. NATO foreign ministers are expected to approve Turkey's request for Patriot anti-missile systems to bolster its defense against possible strikes from neighboring Syria. (AP Photo/Virginia Mayo)

Russia's Foreign Minister Sergey Lavrov speaks at a media conference during a meeting of NATO foreign ministers at NATO headquarters in Brussels on Tuesday, Dec. 4, 2012. NATO foreign ministers are expected to approve Turkey's request for Patriot anti-missile systems to bolster its defense against possible strikes from neighboring Syria. (AP Photo/Yves Logghe)

(AP) ? Syria's civil war is closing in on President Bashar Assad's seat of power in Damascus with clashes between government forces and rebels flaring around the city Tuesday, raising fears the capital will become the next major battlefield in the 20-month-old conflict.

Numerous reports emerged of at least a dozen people killed near the ancient city and elsewhere, and the regime said nine students and a teacher died from rebel mortar fire on a school. The state news agency originally said 30 people had been killed in the attack.

While many of the mostly poor, Sunni Muslim suburbs ringing Damascus have long been opposition hotbeds, fighting has intensified in the area in recent weeks as rebels press a battle they hope will finish Assad's regime.

"The push to take Damascus is a real one, and intense pressure to take control of the city is part of a major strategic shift by rebel commanders," said Mustafa Alani of the Geneva-based Gulf Research Center. "They have realized that without bringing the fight to Damascus, the regime will not collapse."

The increased pressure has raised worries that he or his forces will resort to desperate measures, perhaps striking neighbors Turkey or Israel, or using chemical weapons.

NATO foreign ministers approved Turkey's request for Patriot anti-missile systems to be deployed along its southern border to defend against possible strikes from Syria.

"We stand with Turkey in the spirit of strong solidarity," NATO Secretary-General Anders Fogh Rasmussen told reporters after the meeting in Brussels. "To anyone who would want to attack Turkey, we say, 'Don't even think about it!'"

Before the meeting, Fogh Rasmussen said he expected any use of chemical weapons to get an "immediate reaction from the international community."

On Monday, President Barack Obama said there would be consequences if Assad made the "tragic mistake" of deploying chemical weapons, and Israeli Prime Minister Benjamin Netanyahu said he agreed with the U.S. position.

"We are of the same opinion, that these weapons should not be used and must not reach terror groups," Netanyahu said.

U.S. intelligence has seen signs that Syria is moving materials inside chemical weapons facilities recently, though it is unsure what the movement means. Still, U.S. officials said the White House and its allies are weighing military options should they decide to secure Syria's chemical and biological weapons.

In July, Foreign Ministry spokesman Jihad Makdissi told a news conference that Syria would only use chemical or biological weapons in case of foreign attack, not against its own people. The ministry then tried to blur the issue, saying it had never acknowledged having such weapons.

On Monday, Lebanese security officials said Makdissi had flown from Beirut to London. He has not spoken publicly in weeks and it was unclear whether he had left the government.

NATO foreign ministers also met with their Russian counterpart, Sergey Lavrov. The Kremlin has stymied more than a year of international efforts to apply global pressure on the Assad regime, its strongest ally in the Arab world, but officials say it has expressed equal concern about the threat of any chemical weapons.

Speaking to reporters, Lavrov said Russia wouldn't object to the Patriots.

"We are not trying to interfere with Turkey's right" to defend itself, he said. "We are just saying the threat should not be overstated."

Lavrov stressed that Syrian artillery strikes into Turkey were accidental. And he warned that the conflict "is being increasingly militarized."

Rebel groups around Syria have scored victories in recent weeks, overrunning military bases and airports and halting air traffic at the capital's international airport for days.

The government's response has been harsh, and suburbs to the east and south of Damascus have seen some of the heaviest fighting since July, when rebels seized neighborhoods in the capital itself before being routed by government troops.

Death tolls in the area have soared. On Tuesday, reports emerged of at least four killings of at least a dozen people, all of them near Damascus or in Aleppo, Syria's largest city and a battleground since the summer.

Syria's state news agency SANA said nine students and one teacher were killed when a mortar fired by "terrorists" ? the regime's shorthand for rebels ? hit a ninth grade classroom in the Al-Wafideen area. The housing project, about 25 kilometers (15 miles) northeast of central Damascus, houses 25,000 people displaced from the Golan Heights since the 1967 war between Syria and Israel.

SANA said earlier that 29 students and one teacher had been killed before reporting the lower number.

The opposition Syrian Observatory for Human Rights said 10 were killed and did not specify who fired the mortar.

The Britain-based group, which relies on contacts inside Syria, also said 17 unidentified bodies were found in the southern Damascus suburb of Thiyabiyeh. An activist video posted online showed the dead lined up on a floor, many of their heads bloody. An off-camera voice said they were shot after being detained at government checkpoints.

The Observatory also said 12 others were killed in a shelling attack on the Aleppo neighborhood of Bustan al-Qasr the day before. Online videos showed bloody and dismembered bodies on a sidewalk as people struggled to lift the wounded

Nearby, dozens of men stood in what the unidentified cameraman said was a bread line.

"We still see people standing in a long line despite a massacre to get bread," the cameraman says.

The Observatory also reported 13 dead in a separate attack Monday in Aleppo's Halak neighborhood.

The videos appeared genuine and corresponded to other reports on the incidents. Syria's government severely restricts media access, making independent confirmation nearly impossible.

Syria's uprising began with peaceful protests in March 2011 and later escalated into a civil war that the opposition says has killed more than 40,000 people. So far, both sides have refused international calls for a negotiated solution.

Most analysts agree that the tide is turning, however slowly, against the regime.

But Fyodor Lukyanov, editor of the foreign policy magazine Russia in Global Affairs, said Assad won't leave without a fight.

"Assad realizes that there is no way back for him," said Lukyanov, a leading Russian foreign policy expert with high-level Foreign Ministry connections. "If he tries to jump the boat, his own supporters will not forgive him for doing that. And if he loses, no one will give him any guarantees."

___

Associated Press writers Albert Aji in Damascus, Syria, Barbara Surk in Beirut, Ian Deitch in Jerusalem, Slobodan Lekic in Brussels and Kimberly Dozier and Pauline Jelinek in Washington contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2012-12-04-ML-Syria/id-d284f01617ad4d479e664f63e4cf4bb6

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Monday, December 3, 2012

La. town evacuates; police relocate explosives

NEW ORLEANS (AP) ? A town in northwest Louisiana was being evacuated and state police were starting a criminal investigation of a company after finding about 6 million pounds of explosive material used in howitzers they say was stored illegally.

Boxes and small barrels of the M6 artillery propellant were found both outdoors and crammed into unauthorized buildings leased by Explo Systems Inc. at Camp Minden, the former Louisiana Army Ammunitions Plant, state police superintendent Col. Mike Edmonson said Sunday.

Police were evacuating the town of Doyline, about 270 miles northwest of New Orleans. About half the town's 800 residents left Friday.

The company's "careless and reckless disregard made it unsafe for their own employees, for schoolchildren in Doyline, for the town of Doyline," Edmonson said.

The company is located on a portion of the former ammunition plant's 15,000 acres that is leased for commercial use. Other sections are used for National Guard training.

Capt. Doug Cain, a state police spokesman, identified the product as M6 propellant, used in howitzers and other artillery. The pellets are largely compressed nitrocellulose, also known as guncotton.

Authorities had estimated the total at 1 million tons after an investigator looking into an Oct. 15 explosion at Explo Systems saw cardboard boxes on long rows of pallets behind a building.

They found more stacked in sheds and warehouses when crews returned Saturday to begin moving the boxes into bunkers about two miles away on the former munitions site, which covers nearly 23.5 square miles just north of Doyline.

"It wasn't in their storage magazines. They had it hidden on the property, away from the storage magazines where we would expect to find it," Cain said.

Edmonson said, "It was stuffed in corners. It was stacked all over."

He said that in two days, crews have moved just under a million pounds from the tightest-packed buildings into approved containers and onto 27 tractor-trailers to move to storage bunkers. Another 250,000 pounds has been moved a safe distance from the bulk of the material.

It won't all have to be moved into bunkers to let people return home ? the evacuation could be lifted once the propellant is divided into amounts that won't threaten the town if some ignites, with each area a safe distance from the others, Edmonson said.

Company officials could not be reached Sunday. The owners reportedly are returning Monday from a business trip to South Korea, but the manager has been working with state police from the start, Edmonson said.

Doyline was used to film some scenes for the HBO vampire series "True Blood."

Source: http://news.yahoo.com/la-town-evacuates-police-relocate-explosives-052337453.html

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Scientific American 's 2012 Gadget Guide: Tech That Will Satisfy Your Inner Geek [Slide Show]

Scientific American has combed shopping malls and Web sites for 10 of the geekiest gadgets that leverage science and technology in novel and surprising ways


gadget,camp,stylus,robot,mobile,phoneGADGETS GALORE: Clockwise from the top left square: BioLite CampStove, GoSmart stylus, Sparkfun's Mr. Robot and SpareOne's emergency mobile phone. Image: Courtesy of Scientific American

Two things we love at Scientific American are science and technology?especially in the form of gadgets. When these elements come together in an interesting approach to achieving the mundane?such as keeping your hands warm or charging a mobile phone?we take note. This year's gadget guide includes 10 devices that take advantage of basic science to tackle some particular task in new and fun ways.

Scientific American's 2012 Gadget Guide

Source: http://rss.sciam.com/click.phdo?i=75849507e2767f16779c3a0becc2a662

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